The three-time Oscar nominee passed away in New York of pneumonia brought on by acute myeloid leukemia, her son Jacob Bernstein tells The New York Times.
Nora was was comfortable with romantic comedies as she was with hard-hitting dramas with social themes, Ephron's films featured strong female roles that attracted such A-listers as Meg Ryan, Meryl Streep, Amy Adams and Cher.
The daughter of playwrights and sister to three other writers, Nora was married and divorced to author Dan Greenberg before marrying Watergate investigative reporter Carl Bernstein. She based her searing novel and screenplay Heartburn on the collapse of their marriage.
Ephron's last film was the time-shifting Julia Child foodie flick, Julie & Julia and in 2008 she wrote a bestseller about aging called I Feel Bad About My Neck.
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